Moleculin’s MIRACLE R/R AML Trial Reports Positive Interim Data with 37% Blinded CRc in Venetoclax-Failed Patients

Category: Markets

Published: 2026-07-31T12:10:20.000Z

Moleculin Biotech, Inc. announced positive interim blinded results from Part A of its pivotal Phase 2/3 MIRACLE trial for Annamycin in relapsed or refractory acute myeloid leukemia (R/R AML). The trial shows a 37% composite complete remission (CRc) rate, including in patients who previously failed venetoclax therapy, a significantly higher rate than published salvage remission rates. The company also highlighted the continued absence of cardiotoxicity, differentiating Annamycin from conventional anthracyclines.

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